PHOENIX - With Kevin Love scoring a career-high 29 points, the Bruins nearly frittered away a 21-point halftime lead and hung on to defeat Western Kentucky.
The top-seeded Bruins (34-3) are a win away from their third consecutive trip to the Final Four.
Love also had 14 rebounds. He hit 10-of-14 shots from the floor and helped rescue the Bruins for the second time in as many games. James Keefe had 18 points and 12 rebounds, both career highs for UCLA.
Tyrone Brazelton scored 31 points - 25 in the second half - and Courtney Lee added 18 for 12th-seeded Western Kentucky (29-7).
UCLA led 41-20 at halftime, but the Hilltoppers began pressing and whittled the lead to 61-57 with 6:50 to play. But then Love scored from close range and Josh Shipp hit a 3-pointer to push UCLA's lead to 68-59.
XAVIER 79, WEST VIRGINIA 75 (OT) - In Phoenix, Three-pointers saved Xavier. Missed free throws doomed West Virginia.
B.J. Raymond made two 3-pointers in the last 1:18 of overtime Thursday night and the Musketeers advanced to the West Regional final with a 79-75 victory over coach Bob Huggins' Mountaineers.
Third-seeded Xavier (30-6) will seek its first Final Four appearance when it plays top-seeded UCLA in the regional final on Saturday.
Raymond, who had made only one field goal all night, hit a 3-pointer from the top of the key to put the Musketeers ahead 75-74 with 1:18 to play. He then shook loose on an inbounds play, took a crosscourt pass and made a 3 with the shot clock expiring with 30 seconds to go for a 78-74 lead.
Josh Duncan scored a career-high 26 points, despite foul trouble, to lead Xavier. Joe Alexander scored 18 and had 10 rebounds for the Mountaineers (26-11).
West Virginia missed four of six free throws in the overtime. Alexander missed one with 14.2 seconds left in regulation that would have given his team a 65-64 lead.
East RegionalLouisville 79, Tennessee 60 - In Charlotte, N.C., Earl Clark scored 17 points and had 12 rebounds, and coach Rick Pitino's mix of defenses made life miserable for Tennessee and put the third-seeded Cardinals in the East Regional final.
After two blowout wins last weekend, Pitino's signature zone and pressure limited the high-scoring Volunteers to 34-percent shooting. The veteran coach improved to 8-0 in regional semifinals.
Terrence Williams and Andre McGee each added 13 points and David Padgett had 10 points and eight rebounds for Louisville (27-8), which nearly blew all of a 16-point first half lead, only to take control midway through the second half and keep alive its hopes for a second Final Four berth in four years.
Chris Lofton scored 15 points for Tennessee, but hit only 3 of 15 shots in his final game with the second-seeded Volunteers (31-5), who have never advanced beyond the round of 16.